Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM452RF)

Drug Name
RG7880 Drug Info
Indication
Disease Entry ICD 11 Status REF
Diabetic foot ulcer BD54 Phase 2 [1]
Ulcerative colitis DD71 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DM452RF

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-22 (IL22) TTLDX4N IL22_HUMAN Modulator [3]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Interleukin-22 (IL22) DTT IL22 7.08 5.296 5.423 5.186
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Diabetic foot ulcer
ICD Disease Classification BD54
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin-22 (IL22) DTT IL22 3.69E-03 0.07 0.23
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of Roche.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)