Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM4A92X)

Drug Name
MRL-953 Drug Info
Synonyms SDZ-MRL-953
Indication
Disease Entry ICD 11 Status REF
Immune System disease 4A01-4B41 Terminated [1]
Cross-matching ID
TTD Drug ID
DM4A92X

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin 1 receptor type 2 (IL1R2) TT51DEV IL1R2_HUMAN Agonist [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Interleukin 1 receptor type 2 (IL1R2) DTT IL1R2 5.498 7.408 6.23 2.766
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Immune System disease
ICD Disease Classification 4A01-4B41
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin 1 receptor type 2 (IL1R2) DTT IL1R2 3.43E-01 0.21 0.4
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002036)
2 SDZ MRL 953, a lipid A analog as selective cytokine inducer. Prog Clin Biol Res. 1995;392:549-65.