General Information of Drug (ID: DM4D6ZB)

Drug Name
BMS-1 Drug Info
Synonyms
474429-87-3; Carbamic acid,N-[6-(2-methyl-4,5-diphenyl-1H-imidazol-1-yl)hexyl]-,2-fluorophenyl ester; SCHEMBL1709522; CHEMBL232782; bisarylimidazole derivative, 17; BDBM26758; ZINC1912275; KB-75932; 2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imidazol-1-yl)hexyl]carbamate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
91663303
TTD Drug ID
DM4D6ZB

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fatty acid amide hydrolase (FAAH) TTDP1UC NOUNIPROTAC Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Fatty acid amide hydrolase (FAAH) DTT FAAH 5.744 5.044 4.818 5.984
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Fatty acid amide hydrolase (FAAH) DTT NO-GeName 2.65E-01 0.02 0.1
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Synthesis and evaluation of benzothiazole-based analogues as novel, potent, and selective fatty acid amide hydrolase inhibitors. J Med Chem. 2009 Jan 8;52(1):170-80.