Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM4I6MD)

Drug Name

NICARBAZIN Drug Info

Synonyms

Nicarbazin; 330-95-0; Nicarbazine; Nicrazine; Nicrazin; Nicoxin; Nirazin; Nicarb; Nicarbasin; Nicarbazin [BAN]; MK 75; UNII-11P9NUA12U; MK 75 (VAN); HSDB 7466; NSC 7171; EINECS 206-359-1; AI3-60130; 11P9NUA12U; CHEBI:81725; Urea, N,N'-bis(4-nitrophenyl)-, compd. with 4,6-dimethyl-2(1H)-pyrimidinone (1:1); 4,4'-Dinitrocarbanilide, 4,6-dimethyl-2-pyrimidinol; 1,3-bis(4-nitrophenyl)urea; 4,6-dimethyl-1H-pyrimidin-2-one; N,N'-Bis(4-nitrophenyl)urea compd. with 4,6-dimethyl-2-pyrimidinol (1:1); W-106788

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 9507
ChEBI ID: CHEBI:81725
CAS Number: CAS 330-95-0
TTD Drug ID: DM4I6MD

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Fatty acid amide hydrolase (FAAH)	DTT	FAAH	5.744	5.044	4.818	5.984

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inh... Bioorg Med Chem Lett. 2009 Dec 1;19(23):6793-6.