Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM50ZQP)

Drug Name

2,5-dimethoxy-4-bromophenethylamine Drug Info

Synonyms

2,5-Dimethoxy-4-bromophenethylamine; 4-Bromo-2,5-dimethoxyphenethylamine; 66142-81-2; BDMPEA; 2-(4-Bromo-2,5-dimethoxyphenyl)ethylamine; 2C-B; 2-(4-Bromo-2,5-dimethoxyphenyl)ethanamine; Nexus; 4-Bromo-2,5-dimethoxyphenylethylamine; UNII-V77772N32H; Benzeneethanamine, 4-bromo-2,5-dimethoxy-; CHEMBL292821; 2-CB; CHEBI:189669; V77772N32H; Eros [Street Name]; Venus [Street Name]; Nexus [Street Name]; Nexus (pharmaceutical); Spectrum [Street Name]; NCGC00168259-02; Toonies [Street Name]dd; DEA No. 7392

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 98527
ChEBI ID: CHEBI:189669
CAS Number: CAS 66142-81-2
TTD Drug ID: DM50ZQP

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 2A receptor (HTR2A)	TTJQOD7	5HT2A_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
5-HT 2A receptor (HTR2A)	DTT	HTR2A	4.84	4.904	4.652	4.129

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
5-HT 2A receptor (HTR2A)	DTT	HTR2A	1.68E-01	-0.3	-0.14
5-HT 2A receptor (HTR2A)	DTT	HTR2A	5.59E-01	0.15	0.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agoni... J Med Chem. 2006 Sep 21;49(19):5794-803.