Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM5OHVN)

Drug Name

Lophocladine a Drug Info

Synonyms

Lophocladine A; 887705-27-3; Lophocladines A; 2,7-Naphthyridin-1(2H)-one,4-phenyl-; CHEMBL472895; CTK2I1445; DTXSID90470935; AKOS030621149; 4-phenyl[2,7]naphthyridin-1(2H)-one; 2,7-Naphthyridin-1(2H)-one, 4-phenyl-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 11708368
CAS Number: CAS 887705-27-3
TTD Drug ID: DM5OHVN

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Opioid receptor delta (OPRD1)	TT27RFC	OPRD_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Opioid receptor delta (OPRD1)	DTT	OPRD1	2.848	2.263	1.536	2

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Opioid receptor delta (OPRD1)	DTT	OPRD1	5.52E-01	0.03	0.23

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Lophocladines, bioactive alkaloids from the red alga Lophocladia sp. J Nat Prod. 2006 Apr;69(4):640-4.