Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM5WKU1)

Drug Name
Cardiotrophin-1 Drug Info
Synonyms Cardiotrophin-1 (acute liver failure/obesity/interferon stimulator)
Indication
Disease Entry ICD 11 Status REF
Acute liver failure DB91 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM5WKU1

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cardiotrophin-1 (CTF1) TTXGTZU CTF1_HUMAN Stimulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Cardiotrophin-1 (CTF1) DTT CTF1 5.285 5.372 5.825 6.152
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Acute liver failure
ICD Disease Classification DB91
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cardiotrophin-1 (CTF1) DTT CTF1 1.16E-01 0.22 0.56
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4906).
2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.