Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM62Y1S)

Drug Name

3-bromo-N-(6-methylpyridin-2-yl)benzamide Drug Info

Synonyms

3-bromo-N-(6-methylpyridin-2-yl)benzamide; CHEMBL377195; 188747-28-6; AC1LCNCE; TimTec1_002275; Oprea1_606042; CTK0A3803; DTXSID30345279; MolPort-002-316-872; BOCBDQIZNZCOPX-UHFFFAOYSA-N; HMS1540H09; ZINC138486; STK182187; BDBM50186324; AKOS000204447; MCULE-1961959863; ST031112; 3-bromo-N~1~-(6-methyl-2-pyridyl)benzamide; 3-Bromo-N-(6-methyl-pyridin-2-yl)-benzamide; 3-Bromo-N-(6-methyl-2-pyridinyl)benzamide #; Benzamide, 3-bromo-N-(6-methyl-2-pyridinyl)-; Z57716131; (3-bromophenyl)-N-(6-methyl(2-pyridyl))carboxamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 603306
CAS Number: CAS 188747-28-6
TTD Drug ID: DM62Y1S

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Metabotropic glutamate receptor 5 (mGluR5)	TTHS256	GRM5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Metabotropic glutamate receptor 5 (mGluR5)	DTT	GRM5	3.621	1.888	3.567	4.318

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Metabotropic glutamate receptor 5 (mGluR5)	DTT	GRM5	9.81E-07	-0.26	-0.54

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Design and synthesis of noncompetitive metabotropic glutamate receptor subtype 5 antagonists. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3371-5.