Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM6ESXB)

Drug Name

4-(4-p-Tolylamino-phthalazin-1-yl)-benzamide Drug Info

Synonyms

CHEMBL194747; 4-(4-p-Tolylamino-phthalazin-1-yl)-benzamide; BAS 02999388; AC1LR1JT; Oprea1_289700; Oprea1_093859; SCHEMBL3021915; MolPort-000-702-961; MolPort-001-909-424; ZINC1297142; BDBM50173017; STL148635; STL483208; AKOS005748394; AKOS000665050; MCULE-9763616884; 4-(4-(p-tolylamino)phthalazin-1-yl)benzamide; 4-[4-(4-methylanilino)phthalazin-1-yl]benzamide; 4-{4-[(4-methylphenyl)amino]phthalazin-1-yl}benzamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 1416020
TTD Drug ID: DM6ESXB

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Vascular endothelial growth factor receptor 2 (KDR)	TTUTJGQ	VGFR2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Vascular endothelial growth factor receptor 2 (KDR)	DTT	KDR	1.98E-01	0.11	0.2

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Arylphthalazines: identification of a new phthalazine chemotype as inhibitors of VEGFR kinase. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4696-8.