Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM6GWRB)

Drug Name

6-Phenylsulfanylmethyl-pteridine-2,4-diamine Drug Info

Synonyms

NSC232965; 57963-58-3; UNII-D5VU87D2MN; D5VU87D2MN; 2,4-Diamino-6-phenylthiomethyl-pteridine; CHEMBL279243; 6-(phenylsulfanylmethyl)pteridine-2,4-diamine; 2,4-Pteridinediamine, 6-((phenylthio)methyl)-; 2,4-Pteridinediamine, 6-[(phenylthio)methyl]-; NSC 232965; AC1L7PXP; 6-Phenylsulfanylmethyl-pteridine-2,4-diamine; ZINC5088; SCHEMBL11630631; DTXSID30206699; BDBM50049602; NSC-232965; 6-(Phenylthiomethyl)pteridine-2,4-diamine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 314604
CAS Number: CAS 57963-58-3
TTD Drug ID: DM6GWRB

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Polypeptide deformylase (PDF)	TT9SL3Q	DEFM_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Polypeptide deformylase (PDF)	DTT	PDF	8.87E-16	-0.54	-0.86

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Nonclassical 2,4-diamino-8-deazafolate analogues as inhibitors of dihydrofolate reductases from rat liver, Pneumocystis carinii, and Toxoplasma gon... J Med Chem. 1996 Apr 26;39(9):1836-45.