Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM6TVAX)

• Drug Name: Disulergine Drug Info
• Synonyms: Disulergine; UNII-1Q3CYC1YR6; 1Q3CYC1YR6; CHEMBL95067; 59032-40-5; Disulergina; Disulerginum; Sulergin; disulergine[inn]; Disulergine [INN]; Disulerginum [INN-Latin]; Disulergina [INN-Spanish]; Compound 71; SULERGINE; CM 29717; CH 29-717; CH-29717; AC1Q6V4Q; AC1L2AG4; SCHEMBL1841646; BDBM50130260; CH 29717; N,N-Dimethyl-N'-(6-methylergolin-8alpha-yl)sulfamide; N,N-Dimethyl-N'-((8 alpha)-6-methylergolin-8-yl)sulfamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 68788
  CAS Number: CAS 59032-40-5
  TTD Drug ID: DM6TVAX

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 7 receptor (HTR7)	TTO9X1H	5HT7R_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
5-HT 7 receptor (HTR7)	DTT	HTR7	1.561	1.233	0.848	1.485

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
5-HT 7 receptor (HTR7)	DTT	HTR7	9.79E-01	-0.08	-0.32

References

• [1] Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). J Med Chem. 2003 Jul 3;46(14):2795-812.