Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM6X9J3)

Drug Name

1-(1-Naphthyl)-2-aminopropane Drug Info

Synonyms

CHEMBL471838; 1-(1-Naphthyl)-2-aminopropane; 1-napthyl-2-aminopropane; SCHEMBL266931; AC1L96M0; 1-(1-Naphthyl)propane-2-amine; CTK6A7125; 1-naphthalen-1-ylpropan-2-amine; BDBM50276188; AKOS022488614; AKOS000151865; 12687-37-5; 1-(NAPHTHALEN-1-YL)PROPAN-2-AMINE

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 413939
CAS Number: CAS 12687-37-5
TTD Drug ID: DM6X9J3

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type A (MAO-A)	TT3WG5C	AOFA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type A (MAO-A)	DTT	MAOA	7.207	8.159	9.043	7.711

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type A (MAO-A)	DTT	MAOA	8.14E-01	0.05	0.1

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors. Bioorg Med Chem. 2009 Mar 15;17(6):2452-60.