Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM710KZ)

Drug Name

MG-1101 Drug Info

Synonyms

MBR-193.02; MBRI-93.02; PTH (osteoporosis), Green Cross/BDD/CCDRD; parathyroid gland-secreted peptide (osteoporosis), Green Cross; parathyroid hormone, Green Cross/BDD/CCDRD

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

TTD Drug ID: DM710KZ

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Parathyroid hormone (PTH)	TT6F7GZ	PTHY_HUMAN	Modulator	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Parathyroid hormone (PTH)	DTT	PTH	-0.737	1.485	1.322	0

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Parathyroid hormone (PTH)	DTT	PTH	3.70E-01	0.08	0.66

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Daily parathyroid hormone 1-34 replacement therapy for hypoparathyroidism induces marked changes in bone turnover and structure.J Bone Miner Res.2012 Aug;27(8):1811-20.