Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM72BSO)

Drug Name

N-(2-benzyl),N-(1-methylpyrrol-2-ylmethyl)amine Drug Info

Synonyms

Benzyl-(1-methyl-1H-pyrrol-2-ylmethyl)-amine; 73325-58-3; CHEMBL223300; [(1-methylpyrrol-2-yl)methyl]benzylamine; N-benzyl-1-(1-methyl-1H-pyrrol-2-yl)methanamine; pyrrole inhibitor 18; BAS 10796078; AC1M3ZOX; N-(2-benzyl),N-(1-methylpyrrol-2-ylmethyl)amine; SCHEMBL11567290; CTK6I2711; BDBM15593; MolPort-000-863-754; ZINC2868930; SBB010992; STK511232; BBL030414; 8940AE; AKOS000285009; MCULE-8292930001; ST063683; benzyl[(1-methylpyrrol-2-yl)methyl]amine; TR-044376; KB-250848; benzyl (1-methyl-1h-pyrrol-2-ylmethyl)amine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2222065
TTD Drug ID: DM72BSO

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type A (MAO-A)	TT3WG5C	AOFA_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type A (MAO-A)	DTT	MAOA	7.207	8.159	9.043	7.711

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type A (MAO-A)	DTT	MAOA	8.14E-01	0.05	0.1

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity. J Med Chem. 2007 Mar 8;50(5):922-31.