Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM73F5A)

• Drug Name: 1,2,4-Triazole Drug Info
• Synonyms: 1H-1,2,4-Triazole; 1,2,4-TRIAZOLE; 288-88-0; 4H-1,2,4-triazole; Pyrrodiazole; s-Triazole; 1,2,4-1H-Triazole; 1H-1,2,4-triazol; UNII-10MS0Y1RDI; NSC 83128; 1,2,4 triazole; 1,2,4-triazol; 4H-1,2,4-Triazole (VAN); EINECS 206-022-9; 63598-71-0; 1H-[1,2,4]triazole; 10MS0Y1RDI; AI3-51031; CHEBI:46077; NSPMIYGKQJPBQR-UHFFFAOYSA-N; MFCD00005228; [1,2,4]-triazole; (1,2,4)-triazole; 1,2,4-1H-Triazole, 99.5%; InChI=1/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5; HSDB 7860; 1,4-Triazole; 1,2,4triazole; 1,3,4-triazole; 4H-1,4-Triazole; 1H-1,4-Triazole; 1,2, 4-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 9257
  ChEBI ID: CHEBI:46077
  CAS Number: CAS 288-88-0
  TTD Drug ID: DM73F5A

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase II (CA-II)	DTT	CA2	8.796	10.933	9.395	9.819

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.