Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM7GW4P)

Drug Name

4-oxo-4H-chromene-3-carboxylic acid Drug Info

Synonyms

Chromone-3-carboxylic acid; 39079-62-4; 4-oxo-4H-chromene-3-carboxylic acid; 4-Oxo-4H-1-benzopyran-3-carboxylic acid; 4-oxochromene-3-carboxylic acid; CHEMBL315361; PCIITXGDSHXTSN-UHFFFAOYSA-N; MFCD00017338; Maybridge1_005842; 3-carboxychromone; ACMC-1AD65; SCHEMBL1253672; AC1L49D2; CTK1C4919; ZINC57725; HMS558B12; DTXSID90192327; MolPort-000-145-536; 4-oxo-chromene-3-carboxylic acid; Chromone-3-carboxylic acid, 97%; CC-721; BDBM50131081; 4H-Chromen-4-one-3-carboxylic acid; SBB017525; AKOS001044083; CS-W015906; VZ31583

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 181620
ChEBI ID: CHEBI:166522
CAS Number: CAS 39079-62-4
TTD Drug ID: DM7GW4P

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type B (MAO-B)	TTGP7BY	AOFB_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type B (MAO-B)	DTT	MAOB	9.367	6.907	8.237	8.409

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type B (MAO-B)	DTT	MAOB	2.65E-02	1.12E-02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B. Bioorg Med Chem Lett. 2010 May 1;20(9):2709-12.