Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM7U8ID)

Drug Name

6,7-Diphenyl-pteridine-2,4-diamine Drug Info

Synonyms

6,7-diphenylpteridine-2,4-diamine; 18181-93-6; 2,4-DIAMINO-6,7-DIPHENYL-PTERIDINE; NSC10922; CHEMBL48296; 2,4-Diamino-6,7-diphenylpteridine; AC1Q4WHR; AC1L5CHW; diphenylpteridine-2,4-diamine; SCHEMBL3746280; diaminopteridine derivative, 24; CTK4D7985; BDBM25101; DTXSID80278987; DDZJPETYMUJLIW-UHFFFAOYSA-N; ZINC1712532; NSC-10922; 2,4-Pteridinediamine,6,7-diphenyl-; 6,7-Diphenyl-2,4-pteridinediamine #; 2,4-Pteridinediamine, 6,7-diphenyl-; ACM18181936; DB-081833

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 223355
CAS Number: CAS 18181-93-6
TTD Drug ID: DM7U8ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Polypeptide deformylase (PDF)	TT9SL3Q	DEFM_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Polypeptide deformylase (PDF)	DTT	PDF	8.87E-16	-0.54	-0.86

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three ... J Med Chem. 2003 Apr 24;46(9):1726-36.