Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM7V8DZ)

• Drug Name: Ribose-1-Phosphate Drug Info
• Synonyms: ribose 1-phosphate; ribose-1-phosphate; alpha-D-Ribose 1-phosphate; CHEBI:16300; 1-O-phosphono-alpha-D-ribofuranose; alpha-D-ribofuranose 1-(dihydrogen phosphate); D-ribose-1-phosphate; alpha-D-ribose-1-phosphate; alpha-D-ribofuranose 1-phosphate; R1P; D-ribofuranose 1-(dihydrogen phosphate); 14075-00-4; D-ribose-1P; ribofuranose 1-phosphate; a-D-ribose 1-phosphate; D-ribofuranose 1-phosphate; alpha-D-Ribofuranose, 1-(dihydrogen phosphate); 1-phospho-alpha-D-ribofuranose; CHEMBL603367; SCHEMBL1995711; AC1L96Y2

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 439236
  ChEBI ID: CHEBI:16300
  CAS Number: CAS 14075-00-4
  TTD Drug ID: DM7V8DZ

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Purine nucleoside phosphorylase (PNP)	TTMCF1Y	PNPH_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Purine nucleoside phosphorylase (PNP)	DTT	PNP	7.85	7.15	8.34	8.782

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Purine nucleoside phosphorylase (PNP)	DTT	PNP	3.67E-04	1.95	2.55

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.