Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: )

Drug Name
Drug Info
Synonyms
Indication
Disease Entry ICD 11 Status REF
Idiopathic thrombocytopenic purpura 3B64.10 Approved [1]
Chronic liver disease DB99.0 Phase 3 [1]
Thrombocytopenia 3B64 Phase 2 [1]
Cross-matching ID
TTD Drug ID

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Thrombopoietin receptor (MPL) TTIHYA4 TPOR_HUMAN Agonist [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Thrombopoietin receptor (MPL) DTT MPL 2.7 3.186 2.35 3.766
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Idiopathic thrombocytopenic purpura
ICD Disease Classification 3B64.10
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Thrombopoietin receptor (MPL) DTT MPL 2.61E-06 0.1 0.45
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 022291.
2 Clinical pipeline report, company report or official report of GlaxoSmithKline (2009).