General Information of Drug (ID: DM8MZF4)

Drug Name
P-tolylboronic acid Drug Info
Synonyms
4-Tolylboronic acid; p-Tolylboronic acid; 4-Methylphenylboronic acid; 5720-05-8; (4-methylphenyl)boronic acid; p-Tolueneboronic acid; 4-Methylbenzeneboronic acid; p-Methylbenzeneboronic acid; Boronic acid, (4-methylphenyl)-; Boronic acid, p-tolyl-; Tolyl boronic acid; 4-Methylphenylboric acid; (4-Methylphenyl)Boranediol; 4-methylphenyl boronic acid; 917814-66-5; p-Methylborophenylic acid; p-methylphenylboronic acid; UNII-YJM4GM7K66; YJM4GM7K66; 4-Methyl Phenyl Boronic Acid; CHEMBL140780; BIWQNIMLAISTBV-UHFFFAOYSA-N; NSC 62870
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
79799
CAS Number
CAS 5720-05-8
TTD Drug ID
DM8MZF4

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Carbonic anhydrase (CA) TTUNARX NOUNIPROTAC Inhibitor [1]
Carbonic anhydrase II (CA-II) TTANPDJ CAH2_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Carbonic anhydrase II (CA-II) DTT CA2 8.796 10.933 9.395 9.819
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Carbonic anhydrase II (CA-II) DTT CA2 7.95E-08 0.52 0.33
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Carbonic anhydrase inhibitors. Inhibition of the fungal beta-carbonic anhydrases from Candida albicans and Cryptococcus neoformans with boronic acids. Bioorg Med Chem Lett. 2009 May 15;19(10):2642-5.