Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8STQA)

Drug Name

N-butylresorcinol Drug Info

Synonyms

4-Butylresorcinol; 4-butylbenzene-1,3-diol; 18979-61-8; 4-n-Butylresorcinol; Butylresorcinol; 4-Butylresorcin; N-butylresorcinol; Resorcinol, 4-butyl-; Rucinol; UNII-2IK4UQ3ZGA; 2,4-Dihydroxy-n-butyl benzen; BRN 1942645; 2IK4UQ3ZGA; CHEMBL450195; 2,4-Dihydroxy-N-butyl benzene; CHEBI:81689; AK-81459; Q-200189; Kopcinol; 4-(2,4-dihydroxyphenyl)butane; n-butyl resorcinol; Rucinol (TN); EC 606-191-2; AC1L4FN4; ACMC-1CA91; 1,3-Benzenediol,4-butyl-; SCHEMBL68792; 4-06-00-06003 (Beilstein Handbook Reference); 1,3-Benzenediol, 4-butyl-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 205912
ChEBI ID: CHEBI:81689
CAS Number: CAS 18979-61-8
TTD Drug ID: DM8STQA

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosinase (TYR)	TTULVH8	TYRO_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tyrosinase (TYR)	DTT	TYR	5.959	5.711	5.973	4.912

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tyrosinase (TYR)	DTT	TYR	6.68E-04	2.54	1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Studies on depigmenting activities of dihydroxyl benzamide derivatives containing adamantane moiety. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1532-3.