Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM9W21L)

Drug Name

Ac-WVEHRLKGELSRKGGVV[hArg]KNFVPTDVGPFAF-NH2 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Calcitonin gene-related peptide 1 (CALCA)	TTVSFJW	CALCA_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Calcitonin gene-related peptide 1 (CALCA)	DTT	CALCA	5.221	2.818	4.501	4.647

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Calcitonin gene-related peptide 1 (CALCA)	DTT	CALCA	1.80E-07	-0.32	-0.62

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor. J Med Chem. 2008 Dec 25;51(24):7889-97.