Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM9Y4FL)

Drug Name

Methyl-(1,2,3,4-tetrahydro-naphthalen-1-yl)-amine Drug Info

Synonyms

N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine; 10409-15-1; N-methyl-N-1,2,3,4-tetrahydronaphthalen-1-ylamine; Methyl-(1,2,3,4-tetrahydro-naphthalen-1-yl)-amine; 64037-95-2; ACMC-20mk8d; AC1L2G4R; 1-Naphthalenamine,1,2,3,4-tetrahydro-N-methyl-, (1R)-; SCHEMBL61095; 1-Naphthalenamine, 1,2,3,4-tetrahydro-N-methyl-; AC1Q410F; AC1Q410E; CTK4A2694; DTXSID70275501; JQEUPNKUYMHYPW-UHFFFAOYSA-N; MolPort-001-794-098; HMS1783D04; AKOS017269129; AKOS000118469; ENAMINE-BB EN300-11723; MCULE-6929246555; MB03780; NCGC00338944-02

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 46475
CAS Number: CAS 10409-15-1
TTD Drug ID: DM9Y4FL

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type B (MAO-B)	TTGP7BY	AOFB_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type B (MAO-B)	DTT	MAOB	9.367	6.907	8.237	8.409

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type B (MAO-B)	DTT	MAOB	2.65E-02	1.12E-02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Stereoisomers of allenic amines as inactivators of monoamine oxidase type B. Stereochemical probes of the active site. J Med Chem. 1988 Aug;31(8):1558-66.