Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMAI1HU)

Drug Name
(S)-phenylglycine Drug Info
Synonyms
2935-35-5; H-Phg-Oh; L-Phenylglycine; (S)-2-Amino-2-phenylacetic acid; L-(+)-alpha-Phenylglycine; L-2-Phenylglycine; (2S)-amino(phenyl)acetic acid; L-(+)-2-Phenylglycine; Phenylglycine; (2S)-2-amino-2-phenylacetic acid; L-(+)-alpha-Aminophenylacetic acid; UNII-3I753R0XI6; L-alpha-Phenylglycine; L(+)-alpha-Phenylglycine; (S)-(+)-2-Phenylglycine; CHEMBL378605; (2S)-amino(phenyl)ethanoic acid; CHEBI:439819; 3I753R0XI6; MFCD00064403; (alphaS)-alpha-aminobenzeneacetic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
99291
ChEBI ID
CHEBI:439819
CAS Number
CAS 2935-35-5
TTD Drug ID
DMAI1HU

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) TTFK1JQ CA2D1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) DTT CACNA2D1 5.083 4.833 5.343 2.536
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) DTT CACNA2D1 9.36E-01 -0.03 -0.13
Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) DTT CACNA2D1 2.81E-05 -0.15 -0.68
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41.