Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMAJ85O)

Drug Name
VDA-1102 Drug Info
Indication
Disease Entry ICD 11 Status REF
Actinic keratosis EK90.0 Phase 2 [1]
Cross-matching ID
PubChem CID
76677260
TTD Drug ID
DMAJ85O

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Hexokinase-2 (HK2) TTK02H8 HXK2_HUMAN Modulator [1]
Tissue kallikrein (KLK2) TTJLNAW KLK2_HUMAN Modulator [2]
Voltage-dependent anion channel (VDAC) TTPZI04 NOUNIPROTAC Modulator [2]
Voltage-dependent anion-selective channel 1 (VDAC1) TTAMKGB VDAC1_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Tissue kallikrein (KLK2) DTT KLK2 2.945 2.807 2.744 3.336
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Actinic keratosis
ICD Disease Classification EK90.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tissue kallikrein (KLK2) DTT KLK2 2.30E-01 -0.02 -0.2
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Clinical pipeline report, company report or official report of Vidac Pharma.