Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMB6SNE)

Drug Name

4-(2-Imidazol-1-yl-ethoxy)-benzamide Drug Info

Synonyms

CHEMBL30395; 4-(2-Imidazol-1-yl-ethoxy)-benzamide; SCHEMBL3005716; DVALIYTWWUIPGC-UHFFFAOYSA-N; BDBM50025995; 75912-57-1; 1-[2-(4-carbamoylphenoxy)ethyl]imidazole; 4-(2-(1H-imidazol-1-yl)ethoxy)benzamide; 1-[2-(4-carbamoyl phenoxy)ethyl]imidazole

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 13569177
TTD Drug ID: DMB6SNE

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Steroid 11-beta-hydroxylase (CYP11B1)	TTIQUX7	C11B1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Steroid 11-beta-hydroxylase (CYP11B1)	DTT	CYP11B1	5.647	4.954	5.678	6.194

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Steroid 11-beta-hydroxylase (CYP11B1)	DTT	CYP11B1	4.31E-04	-0.03	-0.13

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Selective thromboxane synthetase inhibitors. 1. 1-[(Aryloxy)alkyl]-1H-imidazoles. J Med Chem. 1985 Oct;28(10):1427-32.