Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMB9OGI)

Drug Name

N-Methyl-N-Propargyl-1(R)-Aminoindan Drug Info

Synonyms

124192-87-6; N-METHYL-N-PROPARGYL-1(R)-AMINOINDAN; (R)-N-Methyl-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine; (R)-2,3-Dihydro-N-methyl-N-2-propynyl-1H-inden-1-amine; (R)-N-Methyl-N-(2-propynyl)-2,3-dihydroinden-1-amine; UNII-1Y7XS87IZR; 1Y7XS87IZR; CHEMBL436947; (1R)-N-methyl-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine; N-[(1S)-2,3-DIHYDRO-1H-INDEN-1-YL]-N-METHYL-N-PROP-2-YNYLAMINE; R-MPAI; N-Methyl-N-2-propynyl-1-indanamine, (R)-; AC1NRD15; 1H-Inden-1-amine,2,3-dihydro-N-methyl-N-2-propyn-1-yl-, (1R)-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5289295
CAS Number: CAS 124192-87-6
TTD Drug ID: DMB9OGI

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type B (MAO-B)	TTGP7BY	AOFB_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type B (MAO-B)	DTT	MAOB	9.367	6.907	8.237	8.409

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type B (MAO-B)	DTT	MAOB	2.65E-02	1.12E-02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.