Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMBKN4P)

Drug Name
Riferminogene pecaplasmid Drug Info
Synonyms Temusi (TN)
Indication
Disease Entry ICD 11 Status REF
Critical limb ischemia BD4Y Discontinued in Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMBKN4P

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heparin-binding growth factor 1 (FGF1) TTMY81X FGF1_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Heparin-binding growth factor 1 (FGF1) DTT FGF1 5.35 4.717 6.95 4.966
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Critical limb ischemia
ICD Disease Classification BD4Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Heparin-binding growth factor 1 (FGF1) DTT FGF1 9.56E-01 -0.02 -0.11
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011879)
2 Riferminogene pecaplasmide. Am J Cardiovasc Drugs. 2010;10(5):343-6.