Details of the Drug

General Information of Drug (ID: DMBKN4P)

Drug Name

Riferminogene pecaplasmid

Synonyms

Temusi (TN)

Indication

Disease Entry	ICD 11	Status	REF
Critical limb ischemia	BD4Y	Discontinued in Phase 3	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Heparin-binding growth factor 1 (FGF1)	TTMY81X	FGF1_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Critical limb ischemia

ICD Disease Classification

BD4Y

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Heparin-binding growth factor 1 (FGF1)	DTT	FGF1	9.56E-01	-0.02	-0.11

Molecular Expression Atlas (MEA)

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011879)
2	Riferminogene pecaplasmide. Am J Cardiovasc Drugs. 2010;10(5):343-6.