Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMCRQTH)

Drug Name
L-371257 Drug Info
Synonyms
162042-44-6; L-371257; L-371,257; CHEMBL24781; L 371257; 1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one; AC1OCFAC; NCGC00159562-01; SCHEMBL4954712; GTPL2252; CTK8E8747; DTXSID30426072; MolPort-023-276-417; ZINC3824080; BDBM50029649; ABP001011; AKOS024457081; API0009977; KB-78045; 1-[4-[(1-ACETYL-4-PIPERIDINYL)OXY]-2-METHOXYBENZOYL]-4-(2-OXO-2H-3,1-BENZOXAZIN-1(4H)-YL)PIPERIDINE; RT-013479; B7045; L014161; L371,257
Cross-matching ID
PubChem CID
6918320
CAS Number
CAS 162042-44-6
TTD Drug ID
DMCRQTH

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Oxytocin receptor (OTR) TTSCIUP OXYR_HUMAN Inhibitor [1]
Vasopressin V1a receptor (V1AR) TT4TFGN V1AR_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Vasopressin V1a receptor (V1AR) DTT AVPR1A 4.689 3.609 4.591 3.878
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Vasopressin V1a receptor (V1AR) DTT AVPR1A 8.89E-04 -0.12 -0.34
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Oral oxytocin antagonists. J Med Chem. 2010 Sep 23;53(18):6525-38.