Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDNJ18)

Drug Name
Efbemalenograstim Drug Info
Synonyms F-627; Recombinant human G-CSF dimer (neutropenia), Generon (Shanghai) Corporation Ltd
Indication
Disease Entry ICD 11 Status REF
Neutropenia 4B00.0 Approved [1]
Cross-matching ID
TTD Drug ID
DMDNJ18

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Granulocyte colony-stimulating factor (CSF3) TT5TQ2W CSF3_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Granulocyte colony-stimulating factor (CSF3) DTT CSF3 1.963 2.07 3.446 2.485
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Neutropenia
ICD Disease Classification 4B00.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Granulocyte colony-stimulating factor (CSF3) DTT CSF3 7.72E-01 -1.68E-03 -0.01
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 761134
2 Clinical pipeline report, company report or official report of Generon (Shanghai) Corporation Ltd.