Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDNPML)

Drug Name

BM-162115 Drug Info

Synonyms

115077-66-2; 1,6-Dioxadispiro[4.1.5.1]trideca-8,11-diene-2,10-dione; 1,6-Dioxadispiro(4.1.5.1)trideca-8,11-diene-2,10-dione; BM 162115; ACMC-20ml0u; BM-162115; BM 16.2115; SCHEMBL8797307; AC1L526V; CTK0I0331

Indication

Disease Entry	ICD 11	Status	REF
Inflammation	1A00-CA43.1	Investigative	[1]

Cross-matching ID

PubChem CID: 196711
CAS Number: CAS 115077-66-2
TTD Drug ID: DMDNPML

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Phospholipase A2 (PLA2G1B)	TT9V5JH	PA21B_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Phospholipase A2 (PLA2G1B)	DTT	PLA2G1B	5.385	3.733	4.178	5.278

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Inflammation

ICD Disease Classification

1A00-CA43.1

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Phospholipase A2 (PLA2G1B)	DTT	PLA2G1B	2.65E-01	-0.08	-0.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Investigation on the effect of experimental phospholipase A2 inhibitors on the formyl-methionyl-leucyl-phenylalanine-stimulated chemotaxis of human leukocytes in vitro. Arzneimittelforschung. 1998 Jan;48(1):77-81.