Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDQWOB)

Drug Name

N-Hydroxy-N-methyl-benzamide Drug Info

Synonyms

N-Hydroxy-N-methylbenzamide; N-Hydroxy-N-methyl-benzamide; benzamide, N-hydroxy-N-methyl-; NSC646164; CHEMBL101043; 2446-50-6; AC1Q5INQ; n-methylbenzohydroxamic acid; AC1L83FX; N-Methyl-N-hydroxybenzamide; SCHEMBL125680; N-benzoyl-N-methylhydroxylamine; CTK0J4869; DTXSID20327327; DDSSLJHUWRMSSP-UHFFFAOYSA-N; ZINC5497333; BDBM50015122; AKOS028111405; NSC-646164

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 371715
CAS Number: CAS 2446-50-6
TTD Drug ID: DMDQWOB

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Arachidonate 5-lipoxygenase (5-LOX)	TT2J34L	LOX5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Arachidonate 5-lipoxygenase (5-LOX)	DTT	ALOX5	4.966	5.133	5.358	6.128

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Arachidonate 5-lipoxygenase (5-LOX)	DTT	ALOX5	4.15E-01	-0.06	-0.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships. J Med Chem. 1990 Mar;33(3):992-8.