Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDUB63)

Drug Name

7-amino-4-hydroxy-2-naphthalenesulfonic acid Drug Info

Synonyms

87-02-5; J acid; 7-AMINO-4-HYDROXY-2-NAPHTHALENESULFONIC ACID; 7-amino-4-hydroxynaphthalene-2-sulfonic acid; Isogamma acid; I acid; 2-Naphthalenesulfonic acid, 7-amino-4-hydroxy-; Kyselina I; 2-Amino-5-naphthol-7-sulfonic Acid; Kyselina I [Czech]; Aminonaphthol sulfonic acid J; 6-Amino-1-naphthol-3-sulfonic acid; CCRIS 8989; EINECS 201-718-9; NSC 31510; Kyselina 2-amino-5-naftol-7-sulfonova; BRN 2217192; UNII-9A1IU1C93L; MLS002638012; CHEMBL220259; 9A1IU1C93L; CHEBI:87316; 7-Amino-4-hydroxynaphthalene-2-sulphonic acid; Kyselina 6

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6868
ChEBI ID: CHEBI:87316
CAS Number: CAS 87-02-5
TTD Drug ID: DMDUB63

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
DNA topoisomerase I (TOP1)	TTGTQHC	TOP1_HUMAN	Binder	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
DNA topoisomerase I (TOP1)	DTT	TOP1	6.65E-01	0.2	0.39

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Comparison of responses of DNA topoisomerase I from Candida albicans and human cells to four new agents which stimulate topoisomerase-dependent DNA nicking. FEMS Microbiol Lett. 1996 May 1;138(2-3):105-11.