Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DME9HNO)

• Drug Name: N-(2-Thienylmethyl)-2,5-Thiophenedisulfonamide Drug Info
• Synonyms: n-(2-thienylmethyl)-2,5-thiophenedisulfonamide; 2-N-(thiophen-2-ylmethyl)thiophene-2,5-disulfonamide; 1bnw; AC1L1HU8; SCHEMBL677620; BDBM11931; STOTVDLYLKWVJB-UHFFFAOYSA-N; AL5415; DB02986; N-(2-Thienyl)methyl-2,5-thiophenedisulfonamide; N-(2-Thienylmethyl)thiophene-2,5-disulfonamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 4293
  TTD Drug ID: DME9HNO

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase II (CA-II)	DTT	CA2	8.796	10.933	9.395	9.819

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.