Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFO1H2)

Drug Name

2,6-di-tert-butyl-4-methoxyphenol Drug Info

Synonyms

2,6-DI-TERT-BUTYL-4-METHOXYPHENOL; 489-01-0; 3,5-Di-tert-butyl-4-hydroxyanisole; Topanol 354; Phenol, 2,6-bis(1,1-dimethylethyl)-4-methoxy-; 3,5-di-t-Butyl-4-hydroxyanisole; UNII-616072TMXY; CCRIS 5219; 2,6-Bis(1,1-dimethylethyl)-4-methoxyphenol; EINECS 207-693-0; NSC 14451; Phenol, 2,6-di-tert-butyl-4-methoxy-; CHEMBL98253; 2,6-di-t-butyl-4-methoxyphenol; SLUKQUGVTITNSY-UHFFFAOYSA-N; 2,6-ditert-butyl-4-methoxyphenol; 616072TMXY; 2,6-bis(tert-butyl)-4-methoxyphenol; 2,6-Di-tert-butyl-4-methoxyphenol, 97%; DTBHA; ACMC-1ALDH

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 10269
CAS Number: CAS 489-01-0
TTD Drug ID: DMFO1H2

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase II (CA-II)	DTT	CA2	8.796	10.933	9.395	9.819

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. Bioorg Med Chem. 2009 Apr 15;17(8):3207-11.