Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFO7CH)

Drug Name

2-(butylthiomethyl)-5-hydroxy-4H-pyran-4-one Drug Info

Synonyms

CHEMBL1269398; 204503-10-6; 2-(butylthiomethyl)-5-hydroxy-4H-pyran-4-one; CTK0J0428; DTXSID10680655; BDBM50330110; AKOS030554091; 4H-Pyran-4-one, 2-[(butylthio)methyl]-5-hydroxy-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 52943048
CAS Number: CAS 204503-10-6
TTD Drug ID: DMFO7CH

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosinase (TYR)	TTULVH8	TYRO_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tyrosinase (TYR)	DTT	TYR	5.959	5.711	5.973	4.912

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tyrosinase (TYR)	DTT	TYR	6.68E-04	2.54	1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Kojyl thioether derivatives having both tyrosinase inhibitory and anti-inflammatory properties. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6569-71.