General Information of Drug (ID: DMFPUGV)

Drug Name
1-(3-Phenylallylidene)thiosemicarbazide Drug Info
Synonyms
Cinnamaldehyde thiosemicarbazone; CHEMBL388025; 5351-70-2; 1-(3-Phenylallylidene)thiosemicarbazide; AC1NVG31; Cinnamaldehydethiosemicarbazone; 3-Phenylpropenalthiosemicarbazone; BDBM50241213; ZINC11536050; 3-phenylacrylaldehyde thiosemicarbazone; AKOS023092594; (Z)-1-((E)-3-phenylallylidene)thiosemicarbazide; AF-960/00472016; [(Z)-[(E)-3-phenylprop-2-enylidene]amino]thiourea; F3111-2831; N'-[(3-phenylprop-2-en-1-ylidene)amino]carbamimidothioic acid; (1Z,N'Z)-N'-((E)-3-phenylallylidene)carbamohydrazonothioic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5559203
TTD Drug ID
DMFPUGV

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tyrosinase (TYR) TTULVH8 TYRO_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Tyrosinase (TYR) DTT TYR 5.959 5.711 5.973 4.912
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tyrosinase (TYR) DTT TYR 6.68E-04 2.54 1.15
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A class of potent tyrosinase inhibitors: alkylidenethiosemicarbazide compounds. Eur J Med Chem. 2009 Apr;44(4):1773-8.