General Information of Drug (ID: DMFY3VS)

Drug Name
1,4-diphenyl-(1E,3E)-1,3-butadiene Drug Info
Synonyms
Bistyryl; 1,4-Diphenyl-1,3-butadiene; 1,4-Diphenylbutadiene; trans,trans-1,4-Diphenyl-1,3-butadiene; 538-81-8; 1,4-Diphenylerythrene; Distyryl; trans,trans-1,4-Diphenylbuta-1,3-diene; (1E,3E)-1,4-Diphenylbuta-1,3-diene; 886-65-7; NSC 122702; 1,4-Diphenylbuta-1,3-diene; UNII-R7P15V6543; 1,1'-(1E,3E)-buta-1,3-diene-1,4-diyldibenzene; 1,3-Butadiene, 1,4-diphenyl-; EINECS 212-952-6; CHEMBL198810; CHEBI:35100; JFLKFZNIIQFQBS-FNCQTZNRSA-N; (4-phenyl-1,3-butadienyl)benzene; R7P15V6543; 1,1'-buta-1,3-diene-1,4-diyldibenzene
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
641683
ChEBI ID
CHEBI:35100
CAS Number
CAS 538-81-8
TTD Drug ID
DMFY3VS

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type B (MAO-B) TTGP7BY AOFB_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Monoamine oxidase type B (MAO-B) DTT MAOB 9.367 6.907 8.237 8.409
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type B (MAO-B) DTT MAOB 2.65E-02 1.12E-02 0.07
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Docking studies on monoamine oxidase-B inhibitors: estimation of inhibition constants (K(i)) of a series of experimentally tested compounds. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4438-46.