Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMGVJBD)

Drug Name

N-Phenyl-5-phenylimidazo[1,5-a]pyrazin-8-amine Drug Info

Synonyms

CHEMBL426903; 849199-96-8; imidazo[1,5-a]pyrazin-8-amine,n,5-diphenyl-; N-Phenyl-5-phenylimidazo[1,5-a]pyrazin-8-amine; CTK3C9676; DTXSID80658947; BDBM50198371; ZINC28642119; KB-273858; Imidazo[1,5-a]pyrazin-8-amine, N,5-diphenyl-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 44422490
CAS Number: CAS 849199-96-8
TTD Drug ID: DMGVJBD

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Proto-oncogene c-Src (SRC)	TT6PKBN	SRC_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Proto-oncogene c-Src (SRC)	DTT	SRC	2.907	3.35	3.498	4.75

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Proto-oncogene c-Src (SRC)	DTT	SRC	6.45E-01	-0.08	-0.58
Proto-oncogene c-Src (SRC)	DTT	SRC	2.08E-03	-0.52	-1.62

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis and c-Src inhibitory activity of imidazo[1,5-a]pyrazine derivatives as an agent for treatment of acute ischemic stroke. Bioorg Med Chem. 2007 Jan 15;15(2):868-85.