Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMHU78R)

Drug Name

6-m-Tolyl-pteridine-2,4,7-triamine Drug Info

Synonyms

6-(3-methylphenyl)pteridine-2,4,7-triamine; 2853-70-5; UNII-Y75RNL3DWL; Y75RNL3DWL; CHEMBL48189; NSC19443; NSC 19443; 6-m-Tolyl-pteridine-2,4,7-triamine; NSC 639358; AC1Q4WBT; AC1L5FLS; CTK4G1672; DTXSID00182754; ZINC1566881; 6-meta-tolylpteridine-2,7-triamine; NSC639358; NSC-19443; BDBM50127144; 6-(m-tolyl)pteridine-2,4,7-triamine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 227595
CAS Number: CAS 2853-70-5
TTD Drug ID: DMHU78R

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Polypeptide deformylase (PDF)	TT9SL3Q	DEFM_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Polypeptide deformylase (PDF)	DTT	PDF	8.87E-16	-0.54	-0.86

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three ... J Med Chem. 2003 Apr 24;46(9):1726-36.