Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMHZCLV)

Drug Name

N-Propargyl-1(S)-Aminoindan Drug Info

Synonyms

185517-74-2; (S)-N-(2-Propynyl)-2,3-dihydroinden-1-amine; TVP1022; N-PROPARGYL-1(S)-AMINOINDAN; (S)-Rasagiline; J-500397; S-PAI; AC1NRD1Z; N-propargyl-1-(s)aminoindan; SCHEMBL332967; CHEMBL1235738; BDBM11000; (S)-N-2-propynyl-1-indanamine; RUOKEQAAGRXIBM-LBPRGKRZSA-N; MolPort-006-666-243; KS-00000LL3; ZINC19875505; ANW-23242; FCH907116; AKOS024256741; TV-1022; DB03894; AJ-75608; AS-32581; HY-14200; CJ-16483; AC-14138; TVP1022, > TC-111987; AB0052190; FT-0694134; FT-0674331; V3968; (1S)-N-methyl-N-prop-2-ynyl-indan-1-amine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5289310
CAS Number: CAS 185517-74-2
TTD Drug ID: DMHZCLV

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type B (MAO-B)	TTGP7BY	AOFB_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type B (MAO-B)	DTT	MAOB	9.367	6.907	8.237	8.409

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type B (MAO-B)	DTT	MAOB	2.65E-02	1.12E-02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.