Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMI2XP1)

Drug Name

L19-IL-2 fusion protein Drug Info

Synonyms

Darleukin; Immunocytokine fusion protein, Bayer Schering; Immunocytokine fusion protein, Philogen; L19-IL-2 fusion protein, Bayer Schering; L19-IL-2 fusion protein, Philogen

Indication

Disease Entry	ICD 11	Status	REF
Lymphoma	2A80-2A86	Phase 2	[1]

Cross-matching ID

TTD Drug ID: DMI2XP1

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukin-2 (IL2)	TTF89GD	IL2_HUMAN	Not Available	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Interleukin-2 (IL2)	DTT	IL2	0.848	4.548	3.548	4.053

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Lymphoma

ICD Disease Classification

2A80-2A86

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Interleukin-2 (IL2)	DTT	IL2	7.64E-01	1.04E-02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026492)
2	National Cancer Institute Drug Dictionary (drug id 665656).