Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMIHJSA)

• Drug Name: 2-Bromoacetyl Group Drug Info
• Synonyms: BROMOACETIC ACID; 2-Bromoacetic acid; 79-08-3; Monobromoacetic acid; Bromoethanoic acid; Acetic acid, bromo-; To NTU; Bromoacetate ion; Acide bromacetique; 2-bromoethanoic acid; 2-Bromoacetyl Group; Monobromessigsaeure; Acetic acid, 2-bromo-; Bromo-acetic acid; Kyselina bromoctova; alpha-Bromoacetic acid; Caswell No. 112A; NSC 141; .alpha.-Bromoacetic acid; Acide bromacetique [French]; Kyselina bromoctova [Czech]; Monobromessigsaeure [German]; CCRIS 7886; UNII-2B3HS32431; Acetic acid, bromo-, (solution); alpha-Bromoethanoic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 6227
  CAS Number: CAS 79-08-3
  TTD Drug ID: DMIHJSA

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin G/H synthase 1 (COX-1)	TT8NGED	PGH1_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	6.09	7.747	6.04	7.023

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	3.97E-03	0.16	0.43

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.