Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJ01D8)

Drug Name
Colforsin daropate hci Drug Info
Synonyms Adehl (TN); Adele (TN)
Indication
Disease Entry ICD 11 Status REF
Asthma CA23 Approved [1]
Cross-matching ID
PubChem CID
444028
ChEBI ID
CHEBI:31429
CAS Number
CAS 138605-00-2
TTD Drug ID
DMJ01D8

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cathelicidin antimicrobial peptide (CAMP) TTULOB6 CAMP_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Cathelicidin antimicrobial peptide (CAMP) DTT CAMP 4.485 3.561 3.263 5.278
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 12 Disease of the respiratory system
Disease Class ICD-11: CA23 Asthma
The Studied Tissue Nasal and bronchial airway
The Studied Disease Asthma [ICD-11:CA23]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cathelicidin antimicrobial peptide (CAMP) DTT CAMP 7.34E-01 -9.06E-04 -1.65E-03
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Cardiovascular and adenylate cyclase stimulating effects of colforsin daropate, a water-soluble forskolin derivative, compared with those of isoproterenol, dopamine and dobutamine. Circ J. 2002 Dec;66(12):1150-4.
2 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.