Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJ2PG1)

Drug Name

VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 Drug Info

Synonyms

CHEMBL525571; alpha-Cgrp (8-37); Val(8)-phe(37)-cgrp; CGRP8-37; CGRP-(8-37); Calcitonin gene-related peptide (8-37); h alpha-CGRP8-37; 8-Val-37-phe-calcitonin gene-related peptide; Calcitonin gene-related peptide, val(8)-phe(37)-; Calcitonin gene-related peptide, valyl(8)-phenylalanine(37)-; BDBM50000743; NCGC00167246-01; CALCITONIN GENE RELATED PEPTIDE (8-37); [Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2] hC; alpha-Calcitonin gene-r

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 16134896
CAS Number: CAS 119911-68-1
TTD Drug ID: DMJ2PG1

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Calcitonin gene-related peptide 1 (CALCA)	TTVSFJW	CALCA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Calcitonin gene-related peptide 1 (CALCA)	DTT	CALCA	5.221	2.818	4.501	4.647

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Calcitonin gene-related peptide 1 (CALCA)	DTT	CALCA	1.80E-07	-0.32	-0.62

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor. J Med Chem. 2008 Dec 25;51(24):7889-97.