General Information of Drug (ID: DMJ73T6)

Drug Name
N-(4-Ethylphenyl)benzo[d]oxazol-2-amine Drug Info
Synonyms
CHEMBL1269619; N-(4-Ethylphenyl)benzo[d]oxazol-2-amine; SCHEMBL11966141; MolPort-009-215-967; BDBM50329392; ZINC32686273; N-(4-Ethylphenyl)benzoxazole-2-amine; AKOS034448323; MCULE-8409538696; SC-56930; N-(4-ethylphenyl)-1,3-benzoxazol-2-amine; BENZOOXAZOL-2-YL-(4-ETHYL-PHENYL)-AMINE; Z55890479
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
39918957
TTD Drug ID
DMJ73T6

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Arachidonate 5-lipoxygenase (5-LOX) TT2J34L LOX5_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Arachidonate 5-lipoxygenase (5-LOX) DTT ALOX5 4.966 5.133 5.358 6.128
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Arachidonate 5-lipoxygenase (5-LOX) DTT ALOX5 4.15E-01 -0.06 -0.15
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Synthesis and evaluation of benzoxazole derivatives as 5-lipoxygenase inhibitors. Bioorg Med Chem. 2010 Nov 1;18(21):7580-5.