Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJ73T6)

Drug Name

N-(4-Ethylphenyl)benzo[d]oxazol-2-amine Drug Info

Synonyms

CHEMBL1269619; N-(4-Ethylphenyl)benzo[d]oxazol-2-amine; SCHEMBL11966141; MolPort-009-215-967; BDBM50329392; ZINC32686273; N-(4-Ethylphenyl)benzoxazole-2-amine; AKOS034448323; MCULE-8409538696; SC-56930; N-(4-ethylphenyl)-1,3-benzoxazol-2-amine; BENZOOXAZOL-2-YL-(4-ETHYL-PHENYL)-AMINE; Z55890479

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 39918957
TTD Drug ID: DMJ73T6

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Arachidonate 5-lipoxygenase (5-LOX)	TT2J34L	LOX5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Arachidonate 5-lipoxygenase (5-LOX)	DTT	ALOX5	4.966	5.133	5.358	6.128

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Arachidonate 5-lipoxygenase (5-LOX)	DTT	ALOX5	4.15E-01	-0.06	-0.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis and evaluation of benzoxazole derivatives as 5-lipoxygenase inhibitors. Bioorg Med Chem. 2010 Nov 1;18(21):7580-5.