Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJ7G0E)

Drug Name

4-hydroxyphenethyl 3,4,5-trihydroxybenzoate Drug Info

Synonyms

CHEMBL147069; 4-hydroxyphenethyl 3,4,5-trihydroxybenzoate; 2-(4-hydroxyphenyl)ethyl 3,4,5-trihydroxybenzoate; AC1NQOM4; SCHEMBL4738028; Gallic acid 4-hydroxyphenethyl ester; BDBM50109690; 2-(4-hydroxyphenyl) ethyl 3,4,5-trihydroxybenzoate; 3,4,5-Trihydroxy-benzoic acid 2-(4-hydroxy-phenyl)-ethyl ester; Benzoic acid, 3,4,5-trihydroxy-, 2-(4-hydroxyphenyl)ethyl ester

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5276405
TTD Drug ID: DMJ7G0E

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosinase (TYR)	TTULVH8	TYRO_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tyrosinase (TYR)	DTT	TYR	5.959	5.711	5.973	4.912

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tyrosinase (TYR)	DTT	TYR	6.68E-04	2.54	1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthetic tyrosyl gallate derivatives as potent melanin formation inhibitors. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5462-4.