Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJBFN0)

Drug Name

1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE Drug Info

Synonyms

2-Ethoxyethyl ether; DIETHYLENE GLYCOL DIETHYL ETHER; 112-36-7; Diethyl carbitol; 1-Ethoxy-2-(2-ethoxyethoxy)ethane; Ethyl diglyme; Bis(2-ethoxyethyl) ether; Diethyldiethylene glycol; 3,6,9-Trioxaundecane; DEGDEE; Ether, bis(2-ethoxyethyl); Ethane, 1,1'-oxybis[2-ethoxy-; 2-(2-Ethoxyethoxy)-1-ethoxyethane; Diethylether diethylenglykolu; HSDB 68; UNII-ZH086O935Z; Ethanol, 2,2'-oxybis-, diethyl ether; Ethane, 1,1'-oxybis(2-ethoxy-; Glycol, diethylene-, diethyl ether; EINECS 203-963-7; Diethylether diethylenglykolu [Czech]

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 8179
ChEBI ID: CHEBI:44664
CAS Number: CAS 112-36-7
TTD Drug ID: DMJBFN0

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acetylcholinesterase (AChE)	TT1RS9F	ACES_HUMAN	Inhibitor	[1]
Bacterial Phosphoenolpyruvate transferase (Bact ptsI)	TTFGVKC	PT1_ECOLI	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Acetylcholinesterase (AChE)	DTT	ACHE	1.678	1.926	1.766	5.252

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Acetylcholinesterase (AChE)	DTT	ACHE	6.39E-02	-1.07	-1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.