Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJCVQN)

Drug Name

1-(3-benzylquinoxalin-2-yl)hydrazine Drug Info

Synonyms

2-benzyl-3-hydrazinoquinoxaline; 223929-23-5; 2-benzyl-3-hydrazinylquinoxaline; CHEMBL379678; 1-(3-benzylquinoxalin-2-yl)hydrazine; AC1LAIMJ; benzylhydrazinoquinoxaline; SCHEMBL7628856; 3-benzyl-2-hydrazinoquinoxaline; KS-00001USU; CTK7F1811; 3-benzylquinoxaline-2-ylhydrazine; DTXSID80333186; MolPort-009-195-340; (3-benzylquinoxalin-2-yl)hydrazine; ZINC6580943; SBB100772; BDBM50179015; 7662AD; AKOS005070001; RTR-063098; RP14269; AJ-56391; TR-063098; 2R-0102

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 488815
CAS Number: CAS 223929-23-5
TTD Drug ID: DMJCVQN

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type A (MAO-A)	TT3WG5C	AOFA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type A (MAO-A)	DTT	MAOA	7.207	8.159	9.043	7.711

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type A (MAO-A)	DTT	MAOA	8.14E-01	0.05	0.1

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis of 3-benzyl-2-substituted quinoxalines as novel monoamine oxidase A inhibitors. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1753-6.